If you have tried all of the solutions and have not solved the problem, initialize the Epson Scan 2 settings using Epson Scan 2 Utility.
Epson Scan 2 Utility is an application that comes with Epson Scan 2.
Start Epson Scan 2 Utility.
Select the Other tab.
Click Reset.
If initialization does not solve the problem, uninstall and re-install Epson Scan 2.